A deep learning pipeline for three-dimensional brain-wide mapping of local neuronal ensembles in teravoxel light-sheet microscopy
Published in Nature Methods, 2025
This paper introduces ACE (artificial intelligence-based cartography of ensembles), an end-to-end pipeline that employs three-dimensional deep learning segmentation models and advanced cluster-wise statistical algorithms to enable unbiased mapping of local neuronal activity and connectivity in teravoxel light-sheet microscopy data.
Published in Nature Methods, Vol. 22, Issue 3, pp. 600–611, 2025.